Selected Scientific Publications From 21^st Century Biochemicals' Customers
Custom Antibodies

Effects of acyl chain length, unsaturation and pH on thermal stability of model discoidal high-density lipoproteins.
Madhumita Guha, Donald L. Gantz, and Olga Gursky. J. Lipid Res., May 2008; 10.1194.

COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.
Alfred G. Tamayo, Ajit Bharti, Carolina Trujillo, Robert Harrison, and John R. Murphy. Proc. Natl. Acad. Sci. , Apr 2008; 105: 5254 - 5259.

Human Macrophage Inflammatory Protein 3?: Protein and Peptide Nuclear Magnetic Resonance Solution Structures, Dimerization, Dynamics, and Anti-Infective Properties.
David I. Chan, Howard N. Hunter, Brian F. Tack, and Hans J. Vogel. Antimicrob. Agents Chemother., Mar 2008; 52: 883 - 894.

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13.
Lata T. Gooljarsingh, Ami Lakdawala, Frank Coppo, Lusong Luo, Gregg B. Fields, Peter J. Tummino, and Richard R. Gontarek. Protein Sci., Jan 2008; 17: 66 - 71.

Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells.
Denis Gingras*, Marisol Michaud, Genevie`ve Di Tomasso, Eric Be´liveau, Carine Nyalendo, Richard Be´liveau. FEBS Letters (2008) 582:399–404

GTP-independent rapid and slow endocytosis at a central synapse.
Jianhua Xu, Benjamin McNeil, Wei Wu, David Nees, Li Bai and Ling-Gang Wu. Nature Neuroscience (2008) 11:1

Cell Culture and Xenograft-Bearing Animal Studies of Radiolabeled Antisense DNA Carrier. Nanoparticles with Streptavidin as a Linker.
Kayoko Nakamura, Yi Wang, Xinrong Liu, Atsushi Kubo, and Donald J. Hnatowich. J. Nucl. Med., Nov 2007; 48: 1845 - 1852.

Novel C5a Agonist-Based Dendritic Cell Vaccine in a Murine Model of Melanoma.
Anthony A. Floreani, Sandra J. Gunselman, Arthur J. Heires, Ralph J. Hauke, Stefano Tarantolo, John D. Jackson. Cell Cycle (2007) 6:22, 2835-2839

Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection.
James D. Brien, Jennifer L. Uhrlaub and Janko Nikolich-Z?ugich. Eur J Immunol. 2007 Jul;37(7):1855-63

Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.
Markus Cornberg, Alex T. Chen, Lee A. Wilkinson, Michael A. Brehm, Sung-Kwon Kim, Claudia Calcagno, Dario Ghersi, Roberto Puzone, Franco Celada, Raymond M. Welsh, and Liisa K. Selin J Clin Invest. (2006) 116(5):1443-56

Steady-state Kinetic Mechanism of PDK1.
Xinxin Gao and Thomas K. Harris J. Biol. Chem., Aug 2006; 281: 21670 - 21681.

Intracellular Trafficking of KA2 Kainate Receptors Mediated by Interactions with Coatomer Protein Complex I (COPI) and 14-3-3 Chaperone Systems.
Pornpun Vivithanaporn, Sheng Yan, and Geoffrey T. Swanson. J. Biol. Chem., Jun 2006; 281: 15475 - 15484.

Mechanism of Substrate Recognition by Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variants Revealed by a Novel Structural Intermediate.
Moses Prabu-Jeyabalan, Ellen A. Nalivaika, Keith Romano, and Celia A. Schiffer. J. Virol., Apr 2006; 80: 3607 - 3616.

Th-Cytotoxic T-Lymphocyte Chimeric Epitopes Extended by N-e-Palmitoyl Lysines Induce Herpes Simplex Virus Type 1-Specific Effector CD8 Tc1 Responses and Protect against Ocular Infection.
Xiuli Zhang, Annie Issagholian, Eric A. Berg, Jordan B. Fishman, Anthony B. Nesburn, and Lbachir BenMohamed. Journal of Virology (2005) 79(24):15289–15301

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
James G. Conway, et al. Proc. Natl. Acad. Sci. , Nov 2005; 102: 16078 - 16083.

A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
Ryan Ratts, Carolina Trujillo, Ajit Bharti, Johanna vanderSpek, Robert Harrison, and John R. Murphy. Proc. Natl. Acad. Sci. , Oct 2005; 102: 15635 - 15640.

Selected Scientific Publications From 21^st Century Biochemicals' Customers
Custom Peptides

Effects of acyl chain length, unsaturation and pH on thermal stability of model discoidal high-density lipoproteins.
Madhumita Guha, Donald L. Gantz, and Olga Gursky. J. Lipid Res., May 2008; 10.1194.

COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.
Alfred G. Tamayo, Ajit Bharti, Carolina Trujillo, Robert Harrison, and John R. Murphy. Proc. Natl. Acad. Sci. , Apr 2008; 105: 5254 - 5259.

Human Macrophage Inflammatory Protein 3?: Protein and Peptide Nuclear Magnetic Resonance Solution Structures, Dimerization, Dynamics, and Anti-Infective Properties.
David I. Chan, Howard N. Hunter, Brian F. Tack, and Hans J. Vogel. Antimicrob. Agents Chemother., Mar 2008; 52: 883 - 894.

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13.
Lata T. Gooljarsingh, Ami Lakdawala, Frank Coppo, Lusong Luo, Gregg B. Fields, Peter J. Tummino, and Richard R. Gontarek. Protein Sci., Jan 2008; 17: 66 - 71.

Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells.
Denis Gingras*, Marisol Michaud, Genevie`ve Di Tomasso, Eric Be´liveau, Carine Nyalendo, Richard Be´liveau. FEBS Letters (2008) 582:399-404

GTP-independent rapid and slow endocytosis at a central synapse.
Jianhua Xu, Benjamin McNeil, Wei Wu, David Nees, Li Bai and Ling-Gang Wu. Nature Neuroscience (2008) 11:1

Cell Culture and Xenograft-Bearing Animal Studies of Radiolabeled Antisense DNA–Carrier. Nanoparticles with Streptavidin as a Linker.
Kayoko Nakamura, Yi Wang, Xinrong Liu, Atsushi Kubo, and Donald J. Hnatowich. J. Nucl. Med., Nov 2007; 48: 1845 - 1852.

Novel C5a Agonist-Based Dendritic Cell Vaccine in a Murine Model of Melanoma.
Anthony A. Floreani, Sandra J. Gunselman, Arthur J. Heires, Ralph J. Hauke, Stefano Tarantolo, John D. Jackson. Cell Cycle (2007) 6:22, 2835-2839

Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection.
James D. Brien, Jennifer L. Uhrlaub and Janko Nikolich-Z?ugich. Eur J Immunol. 2007 Jul;37(7):1855-63

Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.
Markus Cornberg, Alex T. Chen, Lee A. Wilkinson, Michael A. Brehm, Sung-Kwon Kim, Claudia Calcagno, Dario Ghersi, Roberto Puzone, Franco Celada, Raymond M. Welsh, and Liisa K. Selin J Clin Invest. (2006) 116(5):1443-56

Steady-state Kinetic Mechanism of PDK1.
Xinxin Gao and Thomas K. Harris J. Biol. Chem., Aug 2006; 281: 21670 - 21681.

Intracellular Trafficking of KA2 Kainate Receptors Mediated by Interactions with Coatomer Protein Complex I (COPI) and 14-3-3 Chaperone Systems.
Pornpun Vivithanaporn, Sheng Yan, and Geoffrey T. Swanson. J. Biol. Chem., Jun 2006; 281: 15475 - 15484.

Mechanism of Substrate Recognition by Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variants Revealed by a Novel Structural Intermediate.
Moses Prabu-Jeyabalan, Ellen A. Nalivaika, Keith Romano, and Celia A. Schiffer. J. Virol., Apr 2006; 80: 3607 - 3616.

Th-Cytotoxic T-Lymphocyte Chimeric Epitopes Extended by N-e-Palmitoyl Lysines Induce Herpes Simplex Virus Type 1-Specific Effector CD8 Tc1 Responses and Protect against Ocular Infection.
Xiuli Zhang, Annie Issagholian, Eric A. Berg, Jordan B. Fishman, Anthony B. Nesburn, and Lbachir BenMohamed. Journal of Virology (2005) 79(24):15289–15301

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
James G. Conway, et al. Proc. Natl. Acad. Sci. , Nov 2005; 102: 16078 - 16083.

A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
Ryan Ratts, Carolina Trujillo, Ajit Bharti, Johanna vanderSpek, Robert Harrison, and John R. Murphy. Proc. Natl. Acad. Sci. , Oct 2005; 102: 15635 - 15640.